How much does Semax increase BDNF levels?

Research shows Semax can increase brain-derived neurotrophic factor (BDNF) expression by 1.5-2.5 fold in hippocampal regions within hours of administration. Sustained use maintains elevated BDNF levels, supporting ongoing neuroplasticity and cognitive enhancement. <a href='https://pubmed.ncbi.nlm.nih.gov/17234417/' target='_blank'>Molecular studies</a> confirm Semax upregulates BDNF gene transcription through multiple signaling pathways.