Can peptides worsen acid reflux or GERD?

GLP-1 agonists slow gastric emptying which may worsen GERD symptoms in some people, but others improve due to weight loss. Proton pump inhibitors can be used concurrently if needed. <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520897/' target='_blank'>GI effects review</a>