Do weight loss peptides affect thyroid function?

GLP-1 agonists don't directly impact thyroid hormones in most people. However, there's a boxed warning for medullary thyroid cancer risk based on rodent studies (human risk unclear). <a href='https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-investigating-reports-possible-increased-risk-pancreatitis-and' target='_blank'>FDA thyroid warning</a>