Is Cagrilintide more effective than GLP-1 agonists alone?

When combined with semaglutide, cagrilintide produces superior weight loss (up to 17.1%) compared to semaglutide alone (9.8%). The dual mechanism targeting both GLP-1 and amylin pathways appears synergistic. <a href='https://pubmed.ncbi.nlm.nih.gov/35441470/' target='_blank'>PubMed research</a>