What is Tesofensine and how does it cause weight loss?

Tesofensine is a triple monoamine reuptake inhibitor that increases dopamine, norepinephrine, and serotonin levels. Studies show 10-12% weight loss over 24 weeks by reducing appetite and increasing energy expenditure. <a href='https://pubmed.ncbi.nlm.nih.gov/19007233/' target='_blank'>PubMed study</a>