What peptide has the fewest gastrointestinal side effects?

AOD-9604 and MOTS-c have minimal GI effects but also less dramatic weight loss (3-5%). Among GLP-1s, slower titration and lower doses reduce nausea significantly. <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235137/' target='_blank'>Side effect comparison</a>